![]() The study populations included healthy subjects (29 studies), lung disease (nine), heart disease (four), spinal cord injury (SCI, seven), neuromuscular diseases (three), and obesity (four). Resultsįorty-three studies met inclusion criteria. Standing, sitting, supine, and right- and left-side lying positions were studied. Primary outcome measures were forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC, FEV1/FVC), vital capacity (VC), functional residual capacity (FRC), maximal expiratory pressure (PEmax), maximal inspiratory pressure (PImax), peak expiratory flow (PEF), total lung capacity (TLC), residual volume (RV), and diffusing capacity of the lungs for carbon monoxide (DLCO). Studies that were quasi-experimental, pre-post intervention compared ≥2 positions, including sitting or standing and assessed lung function in non-mechanically ventilated subjects aged ≥18 years were included. ![]() MethodsĪ search to identify English-language papers published from 1/1998–12/2017 was conducted using MEDLINE and Google Scholar with key words: body position, lung function, lung mechanics, lung volume, position change, positioning, posture, pulmonary function testing, sitting, standing, supine, ventilation, and ventilatory change. This systematic review investigated the influence of body position on lung function in healthy persons and specific patient groups. Pulmonary function tests (PFTs) are routinely performed in the upright position due to measurement devices and patient comfort.
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